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Processing of Achilles gene effect dependency matrix for computation of common essential genes with CoRe R package
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2
|
15
|
January 19, 2022
|
|
Can DepMap capture the genes which are in the synthetic lethality?
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7
|
181
|
January 19, 2022
|
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Identify conditionally essential genes in clinical subgroups of a specific cancer type
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4
|
53
|
January 7, 2022
|
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Should I take the mean value for cell-line data?
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3
|
45
|
December 22, 2021
|
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Validation of CRISPR KO
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1
|
65
|
December 3, 2021
|
|
Cancer versus non-cancer dependencies
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4
|
1175
|
December 3, 2021
|
|
Genes excluded in DepMap Reporting
|
|
1
|
46
|
November 13, 2021
|
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Download processed data just before Ceres/Chronos
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1
|
48
|
October 26, 2021
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Different number of genes in CERES and Chronos gene effect
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2
|
76
|
September 28, 2021
|
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miRNA and transcripts in 21Q3
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2
|
130
|
September 23, 2021
|
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Raw Read Counts Accession
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9
|
832
|
September 23, 2021
|
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Cas9 activity scores
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2
|
79
|
August 24, 2021
|
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Can CERES score be comparable across cell lines?
|
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1
|
108
|
August 13, 2021
|
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Identify putative drugs and pertubagens that selectively sensitize specific cancer cell lines for translational cancer research
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2
|
160
|
July 17, 2021
|
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CERES score correlation with cell proliferation
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|
8
|
407
|
June 10, 2021
|
|
How to interpret the results about "effect size"
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|
5
|
567
|
June 2, 2021
|
|
Zygosity of CRISPR mediated deletion in Achilles
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|
1
|
92
|
May 3, 2021
|
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Are DEMETER2 suitable for screening without repliated siRNAs?
|
|
1
|
79
|
April 28, 2021
|
|
Which reference genome is used for aligning raw sequencing data?
|
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3
|
223
|
April 20, 2021
|
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Some gene dependency scores are "NA" in DEMETER2 generated matrix
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|
2
|
127
|
March 18, 2021
|
|
The miRNA data in GeCKO screen
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|
3
|
161
|
March 17, 2021
|
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Find "differentially" significant pertubagens that sensitize selectively different cancer cell lines
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|
4
|
338
|
March 6, 2021
|
|
Common essential genes
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|
3
|
891
|
January 16, 2021
|
|
Question about interpreting Gene Effect
|
|
1
|
275
|
December 8, 2020
|
|
How is the probability of dependency different from the gene effect score?
|
|
0
|
300
|
August 13, 2020
|
|
I’m a computationalist and I want gene scores with no copy number corrections or other fancy processing. How can I get them?
|
|
0
|
120
|
August 13, 2020
|
|
What about guides that are in raw_readcounts but aren’t in the guide_gene_map?
|
|
0
|
87
|
August 13, 2020
|
|
What thresholds should I use to decide if a gene is really having a significant effect on a cell line?
|
|
0
|
268
|
August 13, 2020
|
|
What does a positive CERES score mean?
|
|
0
|
585
|
August 13, 2020
|
|
Why are some cell lines not showing up in the results when certain genes are searched in the combined RNAi dataset?
|
|
0
|
95
|
August 13, 2020
|
