Drug-Target validation using CRISPR and PRISM repurposing dataset

Q&A
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Hello, i am working on validating Drug-target screens to validate the hypothesis that the drug is inhibiting the gene product by examining that the gene ko and the drug have similar signatures (effects). however, i am lost to which dataset is more appropriate for building the correlation model between the two profiles as the CRISPRGeneEffect doesn’t contain the LogFold change in contrast to PRISM repurposing dataset.