Gene effect vs dependent cell lines

Q&A
1

Hello,
Is there a way to identify the dependent cell lines sensitive to the CRISPR KO of a given gene based on its corresponding CERES scores? There are less number of cell lines with CERES <-0.5 than what is displayed on the overview tab of a given gene. Eg. in the case of BRCA1: number of dependent cell lines 548, cell lines with CERES less, than -0.5: 474
Should we simply take the first x number of cell lines you categorized as dependent from the CERES table?
Thanks a lot for your support,
Zoltan Spiro

2

Hi Zoltan, see How is the # of Dependent Cell Lines a gene is essential for calculated?