Dear DepMap team,
Would you please help me to understand gene and drug pearson correlation on selected group of cell lines?
For the circled 3 cell lines, it shows that they have similar drug sensitivity to CB-5083, but AURKA gene is most essential to the cell line at the lowest position. Over all, all the cell lines in the image are negative correlated with CB-5083, this means that the more essential AURKA gene is to a cell line, the less sensitive this cell is to CB-5083, am I correct? Thank you!