Data Removed? Navitoclax single agent data

Issues and Bugs
1

As of yesterday, there were several data sets for Navitoclax as a single agent (both Sanger data sets, IC50 and AUC), but today the option to choose navitoclax as a single agent is not available anymore (08Dec2023). Has this data been removed for some specific reason?

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2

No, we have not intentionally removed data from the Sanger datasets. We did however push a release out which had many corrections to our compound annotations and with that new mappings between the various IDs for compounds. It’s possible there was a problem with the updated ID mapping from Sanger’s IDs to our internal IDs.

We’ll investigate what happened with Navitoclax and fix the mapping (assuming what I think is the problem is correct)

Thanks for alerting us to this.

Phil

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3

I just wanted to circle back to this: A fix was deployed which addressed how Sanger compounds were mapped to compounds from other datasets. This has restored showing Navitoclax in the Sanger drug screens.

Thanks,
Phil

4

Thank you Phil, it does indeed look better now.

5

Hi Phil, not sure if you are still monitoring this thread or if it is related to the same issue, but there doesn’t appear to be any single-agent cisplatin data in the new mapping either.

6

Thanks for letting me know. I’ll file this as a bug so we can investigate.