For PRISM 19Q4, secondary screen, I am wondering if we can compute % killing at a required dosage from AUC values. For each drug-cell line pair, we have available fitted curve upper/lower limits & slope.
If I am not mistaken, these two formulas from Corsello et al. 2020 could be the starting points, but am not sure about the next steps as not all variables (eg. E-inf) here are completely clear. Thanks!