Hi team, I downloaded the CCLE_mutations.csv file for my research study, I’m interested in cell lines STK11 mutated. I found out from my literature studies that the line ACH-000785 (NCI-H2126) is actually mutated for STK11 ( exons 4-6 ) but the file does not report this, and also in the portal, it seems like the line is not mutated for this gene. Thank you for the support.
Maria
Hi,
It appears that this line does have mutations on STK11 but they have been filtered out due to high population allele frequency observed in gnomad. Please see our documentation for details on how we filter our variants.
Thanks,
Simone
