Essentiality score calculation

How can we calculate the essentiality score for a given cell line?

I’m afraid I don’t know what a cell line essentiality score is.

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Hi there,

Are you referring to the gene essentiality scores derived from the CRISPR screening data?

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Yes, we are trying to find out the gene essentiality score derived from CRISPR screening data.

We’re using the CERES model. Please see this paper, and this preprint, for more details on the methodology.