Hi! Is there a way to download the “Likely LOF” data in Custom Downloads? I am interested in downloading this data for some genes of interest across all cell lines. However, I am not seeing an easy way to do this. Thank you!
In the next update of the public portal, we’re planning having the option to export subsets from the mutation table in custom downloads, but this is not released yet.
In the meantime, if it’s just for a few genes, you can look up each gene and look at the mutations across cell lines here (BRAF as an example): https://depmap.org/portal/gene/BRAF?tab=characterization&characterization=mutation. You should be able to select the Likely LOF column by clicking the “Show/Hide columns” button.
Other than that, you can also subset from OmicsSomaticMutations.csv in the file downloads page although the file can be quite large.