Continuing the discussion from P value of enriched lineages:
I bring up the previous discussion as I used the exact same method to reproduce the p-value for enriched lineages using 22Q4 data as what plenehan did, but I got a different p-value as well.
In my case, I tested SRA1 gene and performed the t-test comparing “Colon Adenocarcinoma” subtype lineage cell lines to all the other cell lines, resulting in p-value = 0.0004514.
Can you advise on how the p-value of enriched lineages shown in depmap portal was calculated in more detail?
Or it would come in handy if there’s a file for this information, p-value of enriched lineages for each cell line, that can be downloaded.