P of enriched lineages

Q&A
1

Continuing the discussion from P value of enriched lineages:

I bring up the previous discussion as I used the exact same method to reproduce the p-value for enriched lineages using 22Q4 data as what plenehan did, but I got a different p-value as well.

In my case, I tested SRA1 gene and performed the t-test comparing “Colon Adenocarcinoma” subtype lineage cell lines to all the other cell lines, resulting in p-value = 0.0004514.

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Can you advise on how the p-value of enriched lineages shown in depmap portal was calculated in more detail?

Or it would come in handy if there’s a file for this information, p-value of enriched lineages for each cell line, that can be downloaded.

Thanks!