Hello,
I have a question regarding your DepMap Public 24Q2 dataset, specifically about the file OmicsAbsoluteCNGene.csv.
You mentioned the following:
“Genes that overlap with segmental duplication regions and/or are flagged by repeatMasker are masked in this matrix.”
However, upon reviewing some of the masked genes (such as RPL10), I found that they do not appear to meet this criterion. I would like to understand why these genes are absent in OmicsAbsoluteCNGene.csv.
Additionally, I examined some genes that are present (such as RPS9) and noticed they have a significant amount of repeatMasker overlap. I am curious to know why they remain in the dataset given your filtering criteria.
I look forward to your response.
Thank you very much.