Drug sensitivity replicate-level dose


I am confused with the y-axis which represented drug sensitivity replicate-level dose. Does higher value mean higher drug sensitivity? Thank you for the answers.

Hi Fei,

No, the y-axis corresponds to fold-change value relative to the DMSO control, i.e. lower the value means more sensitive to the drug perturbation. But also, I would suggest using replicate collapsed data as opposed to individual replicates (e.g. using AUC values for CTD2 dataset).