I am a little confused regarding the information you have on your website and Sanger’s information. I am refering to your Drug sensitivity IC50 (Sanger GDSC1 and GDSC2) data as well as what Sanger has on their website if you go to compounds and look for a specific drug. Usually, Sanger will present a table like the following:
|Number of cell lines screened|913|
|Maximum IC50 (uM)|2.18e+3|
|Geometric mean (uM)|34.8|
|Minimum IC50 (uM)|0.151|
|Min screening concentration (uM)|0.125|
|Max screening concentration (uM)|32.0|
Maybe this is due to the fact that I need to research more information on IC50 values, but how can an IC50 value be higher than the max screening concentration? Thanks for your help.