Are these two cell lines same?

[pmontgom]

Hello,

The relationship between these two lines is explained in the following post:

[IMPORTANT UPDATE] Fingerprinting data corrections (21Q3 release)

As part of an ongoing effort to update and improve our data analysis pipelines and release processes, we performed a systematic SNP fingerprinting analysis of all the sequencing data used in DepMap, using the Crosscheck tool (Javed et al., 2020). This allowed us to test whether our sequencing data for a given cell line were internally consistent, and whether cell lines identified as genetically matched agreed with annotations for derivative/isogenic models. Wherever possible, we also compared ou…

In short, ACH-001172 and ACH-000232 both look like they are U251MG, however, ACH-001172 shows a distinct CN profile suggesting that it has drifted significantly from U251MG. That led us to decide to keep it registered as a distinct cell line separate from ACH-000232.

Thanks,
Phil