Somatic mutations: coverage for homozygote reference samples

Q&A
1

Hi ! are you planning to add coverage information for the somatic mutations and the homozygote reference samples ?
In the OmicsSomaticMutations.csv from DepMap Public 23Q4, coverage is only available for heterozygotes or homozygotes for the alternative allele.
In some analyses, coverage information is needed for all samples (not only the ones carrying a mutation).
Many thanks for your feedback.

2

Hi,

Can you clarify which columns you are looking at for coverage information? Here’s our documentation for details on the columns: https://storage.googleapis.com/shared-portal-files/Tools/23Q4_Mutation_Pipeline_Documentation.pdf. Would RefCount and AltCount be what you are looking for?

Thanks,
Simone