Hello,
What version does the DepMap portal use currently to annotate a mutation in a cancer cell line with the default setting?
A couple of cell lines showed a different mutation pattern between cBio (broad 2019 data, one mutation on the target gene) and the DepMap portal (what version? No mutation on the target gene.
Could I get some help? Thank you!
Hi,
Can you clarify what you mean by “version”? The DepMap portal by default displays the latest DepMap release, so if that’s what you mean, the datasets you view currently are from 24Q4.
Our mutation calling and annotation pipeline has changed since 2019, so it is expected that there are differences between CCLE 2019 and the current DepMap data. For details, please see the documentation of our current mutation pipeline:
Thanks,
Simone
Good morning,
This was the information that I was looking for.
Thank you very much!
Best regards,
Eun-Jeong
