Breast cancer classification-related matters

sample_info_BCCL_only.csv (8.9 KB)


Hope all is well. I have been working on breast cancer cell lines (BCCL) dataset and noticed that the intrinsic classification (luminals, HER2 amplified and basals) and the molecular markers (HER2, ER) are not consistent with with Dai et al. (2017) paper (Breast Cancer Cell Line Classification and Its Relevance with Breast Tumor Subtyping). Attached above is a comparison between the subtype labelling from his work and that obtained from DepMap.

Could you kindly let me know the whys and hows on their difference?

Many thanks,
A confused student working on breast cancer cell line classification