It looks like a similar question has been asked on the forum. In short, a higher AUC value generally reflects less sensitivity (= more resistance) to the drug. Therefore, if a gene’s expression is positively correlated with the AUC, it means that cells expressing more of that gene tend to be less sensitive (more resistant) to the drug.
SongSong
2
Related topics
| Topic | Replies | Views | Activity | |
|---|---|---|---|---|
| Interpretation of Drug sensitivity AUC and Logfold change value | 8 | 7225 | March 8, 2024 | |
| Difficulty interpreting PRISM Drugs AUC values | 0 | 932 | July 20, 2023 | |
| Gene and Drug Pearson correlation | 11 | 1388 | May 19, 2021 | |
| How to interpret AUC value | 7 | 3004 | January 11, 2022 | |
| How to inverse the AUC value for drug sensitivity screens | 0 | 488 | January 5, 2023 |
