23Q4 ACH-000190 HDMYZ is incorrectly annotated as AML


Could you please update the 23Q4 annotation for the ACH-000190 HDMYZ cell line?

In the 23Q4 DepMap release, HDMYZ is annotated as “Myeloid/AML”.
In DSMZ and Cellosaurus the cell type for HDMYZ is “non-Hodgkin lymphoma”:

DSMZ Origin: established in 1991 from the pleural effusion (rich in Hodgkin/Reed-Sternberg cells) from a 29-year-old patient with nodular sclerosing Hodgkin lymphoma (stage IIIb) refractory to therapy

DSMZ Reference(s):
14371, 14478, 40211

Thank you!


Thank you for your message.

We believe this line was initially misclassified and have reclassified it as is consistent with Cellosaurus “Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be an acute myeloid leukemia cell line (PubMed=29533902).” If you believe this to be incorrect or have any additional information, please let us know.


Hello Samantha,

Thank you very much for the clarification!

Gabriela Alexe