What is relative copy number/copy number ratio?

Q&A
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3

Hi,

Trying to understand in detail how to obtain relative copy number from absolute copy number values using the log2(relative CN + 1) formula:

Example:
A375 cell line, ploidy = 2.76
ENO4 gene, absolute CN = 3

Why is the relative copy number of ENO4 gene in A375 is 1.04

All values are taken from DepMap and CCLE portals…

Thank you

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