CpG site methylation from RRBS

Q&A
1

Hello everyone,

I am wondering is it possible to get methylation values of individual CpG sites from the RRBS data, such as in bedGraph/bigWig format for example? It seems only the mean methylation of 1 KB regions upstream of promoters or of CpG xlusters are available through the DepMap portal. But to produce these files there must be intermediate files with the methylation of individual CpGs I would suppose.

Best,

Richard

2

Hello,

Yes, you are correct. It appears we do have intermediate files, and it does seem like would be valuable to share those. We have now queued it as something to we’d like to make publicly accessible. However, at this time, I don’t have an estimate of when we’ll add these files.

Thanks,
Phil