I previously used the top 100 codependencies for LONP1 in my paper and noticed the top scoring genes have changed quite significantly.
The top scoring CRISPR genes do not agree with the CRISPR score for LONP1, for example PRB3 is the top co dependency, but it does not appear to have the same depletion when you examine it on DepMap. This is the case for multiple top scoring genes, suggesting there is an error in the computation / scoring process.
