# which parameter in which file best describes how sensitive a cell line is to knockout?

**URL:** <https://forum.depmap.org/t/which-parameter-in-which-file-best-describes-how-sensitive-a-cell-line-is-to-knockout/2331>\
**Category:** Q&A\
**Tags:** data\
**Created:** [February 24, 2023, 3:34pm UTC](https://forum.depmap.org/t/which-parameter-in-which-file-best-describes-how-sensitive-a-cell-line-is-to-knockout/2331 "2023-02-24T15:34:03Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![csmatyi](https://avatars.discourse-cdn.com/v4/letter/c/f14d63/32.png) [@csmatyi](https://forum.depmap.org/u/csmatyi)\
**Post date:** [February 24, 2023, 3:34pm UTC](https://forum.depmap.org/t/which-parameter-in-which-file-best-describes-how-sensitive-a-cell-line-is-to-knockout/2331/1 "2023-02-24T15:34:03Z")

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I am looking through all of the files at [DepMap Data Downloads](https://depmap.org/portal/download/all/). It seems that there are so many options it’s hard to decide which file I need. I need information on any kind pf parameter that tells me how easy it is to knock out a given cell line.  
Thanks, csmatyi

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**Author:** ![vidat](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/vidat/32/780_2.png) [@vidat](https://forum.depmap.org/u/vidat)\
**Post date:** [February 25, 2023, 10:06pm UTC](https://forum.depmap.org/t/which-parameter-in-which-file-best-describes-how-sensitive-a-cell-line-is-to-knockout/2331/2 "2023-02-25T22:06:38Z")

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CRISPR gene effect dataset. this recent question could give you more information on [CRISPR gene effect](https://forum.depmap.org/t/crisprgeneeffect-vs-crisprgenedependency/2333)