# Reference genome for mutation data

**URL:** https://forum.depmap.org/t/reference-genome-for-mutation-data/4176
**Category:** Q&A
**Created:** [April 30, 2025, 4:20pm UTC](https://forum.depmap.org/t/reference-genome-for-mutation-data/4176 "2025-04-30T16:20:38Z")
**Posts on this page:** 2
**Page:** 1

<div class="post-metadata">

### Author: ![Cecilia\_Matho](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/cecilia_matho/32/1497_2.png) [@Cecilia\_Matho](https://forum.depmap.org/u/Cecilia_Matho)
#### Post date: [April 30, 2025, 4:20pm UTC](https://forum.depmap.org/t/reference-genome-for-mutation-data/4176/1 "2025-04-30T16:20:38Z")

</div>

Hi, we are looking at the list of mutations for DU145 cell line ( DepMap ID: **ACH-000979** ) and guessing the position is from hg38 genome, can you please confirm this?  
Thank you very much in advance!

---

<div class="post-metadata">

### Author: ![simz](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/simz/32/440_2.png) [@simz](https://forum.depmap.org/u/simz)
#### Post date: [April 30, 2025, 5:12pm UTC](https://forum.depmap.org/t/reference-genome-for-mutation-data/4176/2 "2025-04-30T17:12:10Z")

</div>

Hi,

Correct, all of our mutation calls are based on hg38. For more information on our mutation pipeline, see [https://storage.googleapis.com/shared-portal-files/Tools/24Q4\_Mutation\_Pipeline\_Documentation.pdf](https://storage.googleapis.com/shared-portal-files/Tools/24Q4_Mutation_Pipeline_Documentation.pdf).

Best,  
Simone