# PWR-1E cell line

**URL:** <https://forum.depmap.org/t/pwr-1e-cell-line/2231>\
**Category:** Feedback\
**Created:** [January 25, 2023, 2:21pm UTC](https://forum.depmap.org/t/pwr-1e-cell-line/2231 "2023-01-25T14:21:30Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![19551962199019911993](https://avatars.discourse-cdn.com/v4/letter/1/b782af/32.png) [@19551962199019911993](https://forum.depmap.org/u/19551962199019911993)\
**Post date:** [January 25, 2023, 2:21pm UTC](https://forum.depmap.org/t/pwr-1e-cell-line/2231/1 "2023-01-25T14:21:30Z")

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Hello! DEPMAP categorizes the PWR-1E cell line as prostate adenocarcinoma under disease whereas all publications I have come across consider it a nor mal cell line. Please could you clarify?

Find below links to some publications

> **[Abstract 128: Effects of NSAIDs on gene expression of small leucine-rich...](https://aacrjournals.org/cancerres/article/79/13_Supplement/128/633453?casa_token=I5O0Ke6wY18AAAAA:dI_KGLO4ZKAtNDWXCpRSFBCwIPOR5SAX_7DM-BjdGvSMAgPOPw5W-axKb4r1h1ZGsCDxF5arMQ)**
>
> Abstract. Background: Malignant transformation has been shown to be favored by the interaction between cancer cells and the tumor microenvironment, with a special role attributed to molecular components present in both compartments, such as...

> **[Atypical chemokine receptor CCRL2 is overexpressed in prostate cancer cells](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352880/)**
>
> Atypical chemokine receptors have recently emerged as important molecular players in health and diseases; they affect chemokine availability and function and impact a multitude of pathophysiological events, including the tumorigenesis process. This...

[https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/bab.2062?casa\_token=IkWr598sm5YAAAAA%3AgJRsYiytk2IY1hqapVARs1yXT4etAAk8qImEUS\_3dvWjNNgwnhwum7WenEn0E3uM3nvqCPr\_9tdW7bv32w](https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/bab.2062?casa_token=IkWr598sm5YAAAAA%3AgJRsYiytk2IY1hqapVARs1yXT4etAAk8qImEUS_3dvWjNNgwnhwum7WenEn0E3uM3nvqCPr_9tdW7bv32w)

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**Author:** ![Samantha\_Stokes](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/samantha_stokes/32/676_2.png) [@Samantha\_Stokes](https://forum.depmap.org/u/Samantha_Stokes)\
**Post date:** [February 6, 2023, 2:01pm UTC](https://forum.depmap.org/t/pwr-1e-cell-line/2231/2 "2023-02-06T14:01:21Z")

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Hello,

Thank you very much for your post! You are correct. We will be updating this annotation in our next release. We apologize for any confusion in the meantime.

Best,  
Samantha