# P of enriched lineages 

**URL:** <https://forum.depmap.org/t/p-of-enriched-lineages/2307>\
**Category:** Q&A\
**Created:** [February 18, 2023, 5:06pm UTC](https://forum.depmap.org/t/p-of-enriched-lineages/2307 "2023-02-18T17:06:59Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![Woori\_Kim](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/woori_kim/32/781_2.png) [@Woori\_Kim](https://forum.depmap.org/u/Woori_Kim)\
**Post date:** [February 18, 2023, 5:06pm UTC](https://forum.depmap.org/t/p-of-enriched-lineages/2307/1 "2023-02-18T17:06:59Z")

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Continuing the discussion from [P value of enriched lineages](https://forum.depmap.org/t/p-value-of-enriched-lineages/549):

I bring up the previous discussion as I used the exact same method to reproduce the p-value for enriched lineages using 22Q4 data as what [plenehan](https://forum.depmap.org/u/plenehan) did, but I got a different p-value as well.

In my case, I tested SRA1 gene and performed the t-test comparing “Colon Adenocarcinoma” subtype lineage cell lines to all the other cell lines, resulting in p-value = 0.0004514.

 ![image](https://canada1.discourse-cdn.com/flex035/uploads/depmap/original/1X/6c8647558d66e1d703d6681a77c9c3198b112b10.png)

Can you advise on how the p-value of enriched lineages shown in depmap portal was calculated in more detail?

Or it would come in handy if there’s a file for this information, p-value of enriched lineages for each cell line, that can be downloaded.

Thanks!