# NF1 KD effects in KRAS mutant cell lines, which dataset to use?

**URL:** https://forum.depmap.org/t/nf1-kd-effects-in-kras-mutant-cell-lines-which-dataset-to-use/729
**Category:** Q&A
**Created:** [July 10, 2021, 8:52pm UTC](https://forum.depmap.org/t/nf1-kd-effects-in-kras-mutant-cell-lines-which-dataset-to-use/729 "2021-07-10T20:52:28Z")
**Posts on this page:** 2
**Page:** 1

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### Author: ![hadderley](https://avatars.discourse-cdn.com/v4/letter/h/2acd7d/32.png) [@hadderley](https://forum.depmap.org/u/hadderley)
#### Post date: [July 10, 2021, 8:52pm UTC](https://forum.depmap.org/t/nf1-kd-effects-in-kras-mutant-cell-lines-which-dataset-to-use/729/1 "2021-07-10T20:52:28Z")

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Hi There,

Im looking for some advice on which dataset to use when assesing CRISPR KD of NF1 in KRAS mutant cell lines by CEREs score, should i be using the dataset named: **CRISPR(Depmap 21q2 Public+score, CERES)** or CRISPR(Depmap 21Q2, Public, CERES) what is the difference between the two?

Many thanks

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### Author: ![Joshua\_Dempster](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/joshua_dempster/32/19_2.png) [@Joshua\_Dempster](https://forum.depmap.org/u/Joshua_Dempster)
#### Post date: [July 26, 2021, 1:31pm UTC](https://forum.depmap.org/t/nf1-kd-effects-in-kras-mutant-cell-lines-which-dataset-to-use/729/2 "2021-07-26T13:31:36Z")

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Public+score is a combined dataset of Project Achilles and Project Score data. It is larger and should be the default for most applications.