# Label cell lines based on TP53 mutation

**URL:** <https://forum.depmap.org/t/label-cell-lines-based-on-tp53-mutation/4459>\
**Category:** Issues and Bugs\
**Tags:** omics\
**Created:** [September 7, 2025, 1:11pm UTC](https://forum.depmap.org/t/label-cell-lines-based-on-tp53-mutation/4459 "2025-09-07T13:11:42Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Abofazl\_Arab](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/abofazl_arab/32/1603_2.png) [@Abofazl\_Arab](https://forum.depmap.org/u/Abofazl_Arab)\
**Post date:** [September 7, 2025, 1:11pm UTC](https://forum.depmap.org/t/label-cell-lines-based-on-tp53-mutation/4459/1 "2025-09-07T13:11:42Z")

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I’m trying to systematically annotated cell lines based on TP53 mutation status for my research. Looking at the potential “wild type” p53 cell lines (i.e. no p53 mutation report in WGS mutation tables), I noticed HL-60 and it made me concerned because HL-60 is a TP53(del) cell lines (you also annotated that in the “PatientSubtypeFeatures” column!). Any thoghts?!

 ![image](https://canada1.discourse-cdn.com/flex035/uploads/depmap/original/2X/7/75990f6257a5d229ead11426394b56c4c38549e8.png)

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**Author:** ![simz](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/simz/32/440_2.png) [@simz](https://forum.depmap.org/u/simz)\
**Post date:** [September 8, 2025, 2:34pm UTC](https://forum.depmap.org/t/label-cell-lines-based-on-tp53-mutation/4459/2 "2025-09-08T14:34:19Z")

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Hi,

Please see reply in [SJSA-1 TP53 status - #7 by simz](https://forum.depmap.org/t/sjsa-1-tp53-status/429/7) .

Simone