# comparison between raw counts and log TPM values

**URL:** <https://forum.depmap.org/t/comparison-between-raw-counts-and-log-tpm-values/4340>\
**Category:** Q&A\
**Created:** [July 10, 2025, 2:16pm UTC](https://forum.depmap.org/t/comparison-between-raw-counts-and-log-tpm-values/4340 "2025-07-10T14:16:09Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![Abed\_Kurdi](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/abed_kurdi/32/1553_2.png) [@Abed\_Kurdi](https://forum.depmap.org/u/Abed_Kurdi)\
**Post date:** [July 10, 2025, 2:16pm UTC](https://forum.depmap.org/t/comparison-between-raw-counts-and-log-tpm-values/4340/1 "2025-07-10T14:16:09Z")

</div>

Hello there,

I downloaded first the log TPM values and plotted them for a specific gene and found that it is expressed. Then, I have to use another normalization method and downloaded the raw counts. Checking the raw counts of this exact same gene in the same cell line, I found it zero.

How can this be explained?

the files I downloaded: OmicsExpressionTPMLogp1HumanAllGenes.csv and OmicsExpressionRawReadCountHumanAllGenesStranded.csv.

Thank you in advance.