# Cell STRAINER documentation

**URL:** <https://forum.depmap.org/t/cell-strainer-documentation/893>\
**Category:** Q&A\
**Tags:** documentation\
**Created:** [September 16, 2021, 9:47am UTC](https://forum.depmap.org/t/cell-strainer-documentation/893 "2021-09-16T09:47:02Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![blas](https://avatars.discourse-cdn.com/v4/letter/b/8e8cbc/32.png) [@blas](https://forum.depmap.org/u/blas)\
**Post date:** [September 16, 2021, 9:47am UTC](https://forum.depmap.org/t/cell-strainer-documentation/893/1 "2021-09-16T09:47:02Z")

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Hello,

I know Cell STRAINER tool uses Pearson’s R correlation between the uploaded copy-number values and those of the mathched CCLE line, but I can’t find documentation on how this calculation is performed. Do you know where I can find it?

Thanks in advance,

Blas.

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**Author:** ![pmontgom](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/pmontgom/32/4_2.png) [@pmontgom](https://forum.depmap.org/u/pmontgom)\
**Post date:** [September 16, 2021, 1:32pm UTC](https://forum.depmap.org/t/cell-strainer-documentation/893/2 "2021-09-16T13:32:12Z")

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Cell STRAINER was described in the paper [Genetic and transcriptional evolution alters cancer cell line drug response | Nature](https://www.nature.com/articles/s41586-018-0409-3). If you have additional questions about the methodology not covered in the paper, I’d recommend contacting the authors of that paper.

Thanks,  
Phil