# cell model passport and depmap has different mutation

**URL:** <https://forum.depmap.org/t/cell-model-passport-and-depmap-has-different-mutation/1967>\
**Category:** Q&A\
**Created:** [October 21, 2022, 6:31pm UTC](https://forum.depmap.org/t/cell-model-passport-and-depmap-has-different-mutation/1967 "2022-10-21T18:31:50Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![yumaomaizi](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/yumaomaizi/32/640_2.png) [@yumaomaizi](https://forum.depmap.org/u/yumaomaizi)\
**Post date:** [October 21, 2022, 6:31pm UTC](https://forum.depmap.org/t/cell-model-passport-and-depmap-has-different-mutation/1967/1 "2022-10-21T18:31:50Z")

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Hi,

I’v searched NFE2L2 gene mutation in LK2 cellline through [Cell Model Passports](https://cellmodelpassports.sanger.ac.uk/passports/SIDM00548), the mutation is: **p.E79K** , And i also download DepMap CCLE\_mutations.csv file, and search by _Hugo\_Symbol == ‘NFE2L2’, DepMap\_ID == ‘ACH-000769’_, but the mutation is: **p.E63K**.

So, what’s the difference? Thanks!!

I wondered maybe they mapped of the mutation to different Annotation Transcripts?