# Cell lines previously found do not appear in the same  gene analysis 

**URL:** <https://forum.depmap.org/t/cell-lines-previously-found-do-not-appear-in-the-same-gene-analysis/2139>\
**Category:** Issues and Bugs\
**Created:** [December 17, 2022, 7:57pm UTC](https://forum.depmap.org/t/cell-lines-previously-found-do-not-appear-in-the-same-gene-analysis/2139 "2022-12-17T19:57:36Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![PatriciaG](https://avatars.discourse-cdn.com/v4/letter/p/2acd7d/32.png) [@PatriciaG](https://forum.depmap.org/u/PatriciaG)\
**Post date:** [December 17, 2022, 7:57pm UTC](https://forum.depmap.org/t/cell-lines-previously-found-do-not-appear-in-the-same-gene-analysis/2139/1 "2022-12-17T19:57:36Z")

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I search information of VDAC2 at 2 days interval and the results are not the same. In Enriched Lineages, I found Multiple myeloma and plasma cell as the top dependent cells on december 14th . Surprisingly, today (december 16th) for te same gene, Melanoma, Skin and plasma cell myeloma appeared instead of what I found in the first query (screenshoot of 2 queries are enclosed). While clikining in “view details”, myeloma cells are not present anymore, while n=21 myeloma cell lines were identified in the first query. Could you explain me what did it happen? which results are reliable?

 ![Overview VDAC2 2022-12-14 à 11.20.00](https://canada1.discourse-cdn.com/flex035/uploads/depmap/original/1X/a96ee2fa80a6f2fbf3f4669a8aa838af1aad0cb0.png)  
 ![Overview VDAC2 2022-12-16 à 11.01.06](https://canada1.discourse-cdn.com/flex035/uploads/depmap/original/1X/e08e187579ec50b6722ce5eb055f61bfc66a1fbb.png)

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**Author:** ![pmontgom](https://yyz1.discourse-cdn.com/flex035/user_avatar/forum.depmap.org/pmontgom/32/4_2.png) [@pmontgom](https://forum.depmap.org/u/pmontgom)\
**Post date:** [December 20, 2022, 7:32pm UTC](https://forum.depmap.org/t/cell-lines-previously-found-do-not-appear-in-the-same-gene-analysis/2139/2 "2022-12-20T19:32:43Z")

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I believe the difference you’re seeing is because on Dec 14th the portal and the depmap data was updated ( [Announcing the 22Q4 Release!](https://forum.depmap.org/t/announcing-the-22q4-release/2125) )

Data was reprocessed using our latest pipelines, but I suspect the difference you’re referring to is due our switch to using OncoTree’s nomenclature instead of the labels we’d been using previously.